MOL3023 Molekylær medisinsk bakteriologi

Knowledge

After completion of the course the student should be able to:

• Demonstrate advanced knowledge about the molecular biology of bacteria including mobile genomic elements and their role in bacterial adaptation.
• Demonstrate good knowledge about important bacterial pathogens, including epidemiology and role in infection
• Demonstrate advanced knowledge about molecular methods for detection of bacterial infections
• Demonstrate advanced knowledge about molecular methods for genotyping of bacteria, and their use in surveillance, transmission and outbreak investigation of bacterial infectious diseases
• Demonstrate basic knowledge about bioinformatics methods used for quality control, assembly, in silico typing and detection of resistance and virulence genes in bacteria
• Demonstrate basic knowledge about the human microbiome and metagenomics methods for microbiome analyses

Skills

After completion of the course the student shall be able to:

• Choose appropriate methods to use for identification and genotyping based on bacterial species and type of clinical problem
• Evaluate and compare different methods used for sequencing
• Interpret results from genotyping in a clinical context
• Perform basic bioinformatics analyses on bacterial genomes
• Perform quality control, evaluate and interpret results from bioinformatics analyses

General competence

After completion of the course the student shall be able to:

• Demonstrate an advanced understanding of the most common bacterial pathogens as well as the molecular methods used for detection and genotyping in medical microbiology
• Evaluate and select appropriate methods to be used in a molecular medical microbiology laboratory

Compulsory activity: A bioinformatics exercise must be approved before the student can take the written exam. Written exam count 100 % of the final grade.

Retake of exam: If the compulsory bioinformatics exercise has been approved in a previous semester, it is sufficient to retake the written exam. If the bioinformatics excercise is not passed, the excercise must be resubmitted and approved before the written exam can be re-taken. Students with legitimate leave of absence at the final examination and students who receive the grade F make re-sit the examination in the following semester.

The language of instruction is English. The compulsory bioinformatics exercise and the written exam must be answered in English.