MOL3005 Immunologi

Knowledge

After the course, the candidate:

• has a broad knowledge of central processes in innate and adaptive immunity at a cellular and molecular level
• can explain how the immune system discriminates between self, non-self and altered self
• has advanced knowledge of the main mechanisms and consequences of inflammation
• has understood the genetic basis for immunological diversity and the generation of adaptive immune responses
• has advanced knowledge of the principles governing vaccination and the mechanisms of protection against infectious diseases
• can explain the basis of immunological tolerance, autoimmunity and transplantation
• can outline key events and cellular players governing mucosal immunity
• can describe the immunological basis of allergy and allergic diseases
• has knowledge on the role of the immune system in cancer; tumor immunology and the principles of immunotherapy

Skills

After the course, the candidate can:

• compare the key mechanisms and cellular players of innate and adaptive immunity and interpret how they interfere with each other
• critically assess how immune functions contribute to host defense as well as pathologies and how immune functions are regulated
• outline how the nature of an antigenic structure will shape the resulting immune effector responses
• collect, evaluate and interpret relevant information from scientific literature related to immunological topics and summarize the information in written form

General proficiency

After the course, the candidate can:

• apply knowledge from the course to discuss immunological questions as well as to read and interpret scientific literature on immunological topics
• communicate how the complex network of immune functions contributes to host defense as well as pathologies
• independently and critically engage with immunological topics and summarize and present them in written form

Written exam. The exam must be answered in English language.

Compulsory assignment: Written essay on a given immunological topic. Completion of the mandatory assignment is a prerequisite to be admitted to the exam.

Retake of the exam: Students with legitimate leave of absence at the final examination and students who receive the grade F may retake the exam the following semester. Completion of the compulsory assignment in a previous semester may be approved by the department.

Suggested textbook: Janeway`s Immunobiology (10th edition, ISBN 9781315533247).

Kuby Immunology (8th edition, ISBN 9781319114701) is a comparable alternative.

The syllabus of the course is defined by the learning objectives. The course is based on weekly lectures throughout the semester and optional group colloquia. The course includes writing of a compulsory assignment in which a specified immunological topic is reviewed.

The language of teaching and examination is English.