MOL8009 Molekylærmekanismer for inflammasjon

Knowledge

After completing the course, the candidate:

• has insight into basic mechanisms of inflammation, much of this in relation to research conducted at IKOM
• has advanced knowledge of how the body fights infection with many classes of pathogens, both concerning different cell types involved and recognition mechanisms and signaling pathways within those cells.
• can evaluate similarities and differences between sterile inflammation and inflammation induced by infections.
• has increased understanding of how research on molecular inflammation can contribute to the development of vaccines, therapies, and disease prevention.

Skills

After the course, the candidate can:

• identify and critically assess key signals of inflammation
• has advanced knowledge of central signaling pathways of innate immunity
• outline, evaluate and interpret how certain ligands and signals are associated with specific classes of microbial pathogens, diseases, and inflammatory conditions.
• Has an advanced understanding of the processes how innate immunity shapes and directs the development and outcome of adaptive immune responses

General proficiency

After the course, the candidate can:

• Comprehend and interpret how inflammatory signals can be both beneficial and harmful for the body, depending on the circumstances, such as the nature of acute vs chronic inflammation.
• Discuss and compare differences and similarities between different types of inflammation and innate immune signals
• Interpret and critically evaluate scientific literature on topics of inflammation, innate immunity and the relationship to disease

Compulsory assignments

• Attendance in lectures (minimum 80% must be attended) and group discussions
• Group work and presentation

Completion of the compulsory assignments is a prerequisite to be admitted to the exam.

Exam

Evaluation will be on a short paper, written in English.

Re-sit of the exam: Students with legitimate leave of absence at the final examination and students who do not pass the exam may re-sit the exam the following semester. Approved compulsory assignments from a previous semester may be approved by the department.

Suggested textbooks for background reading:

Janeway`s Immunobiology (10th edition, ISBN 9781315533247).

Kuby Immunology (8th edition, ISBN 9781319114701) is a comparable alternative.

Specific background literature related to different lectures and sessions will be distributed before and during the course.